Writing & StyleStyle guide

IMRAD Manuscript Structure

Use IMRAD as the default high-level structure for many original-research manuscripts: Introduction, Methods, Results, and Discussion. IMRAD is common for original research, not universal. Reviews, case reports, editorials, and journal-specific formats may require a different structure.

Quick answer

Use IMRAD as the default high-level structure for many original-research manuscripts: Introduction, Methods, Results, and Discussion.

Key details

Core IssueICMJE states that original-research articles are usually organized as Introduction, Methods, Results, and Discussion (IMRAD), reflecting the research process rather than an arbitrary format.
Registerscholarly, professional, or research/report writing

Important caveats

Scope Boundary

IMRAD is common for original research, not universal. Reviews, case reports, editorials, and journal-specific formats may require a different structure.

Further guidance

Content

Map background and objective to Introduction, reproducible procedures to Methods, findings to Results, and interpretation/limitations to Discussion; use subheadings where useful.

Purpose

Give research manuscripts a familiar evidence-flow structure that helps readers locate rationale, methods, findings, and interpretation.

Sources and evidence

Sources are shown with the role they play in this guide. Historical or style-sensitive claims are kept within the evidence boundary described above.

  1. Preparing a Manuscript for Submission to a Medical Journal — ICMJE (opens in a new tab)International Committee of Medical Journal Editors (ICMJE) · ICMJE manuscript-submission guidance on reporting sources of support/funding that facilitated the work

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