Writing & StyleStyle guide

IMRAD Manuscript Structure

Use IMRAD as the default high-level structure for many original-research manuscripts: Introduction, Methods, Results, and Discussion. IMRAD is common for original research, not universal. Reviews, case reports, editorials, and journal-specific formats may require a different structure.

Quick answer

Use IMRAD as the default high-level structure for many original-research manuscripts: Introduction, Methods, Results, and Discussion.

Key details

Core IssueICMJE states that original-research articles are usually organized as Introduction, Methods, Results, and Discussion (IMRAD), reflecting the research process rather than an arbitrary format.
Registerscholarly, professional, or research/report writing

Important caveats

Scope Boundary

IMRAD is common for original research, not universal. Reviews, case reports, editorials, and journal-specific formats may require a different structure.

Further guidance

Content

Map background and objective to Introduction, reproducible procedures to Methods, findings to Results, and interpretation/limitations to Discussion; use subheadings where useful.

Practical Application

For an original-research manuscript that follows IMRAD, map the research problem and objective to Introduction, reproducible procedures to Methods, findings to Results, and interpretation/implications to Discussion. Follow the target journal when it combines or renames sections.

Purpose

Give research manuscripts a familiar evidence-flow structure that helps readers locate rationale, methods, findings, and interpretation.

Reader Check

Can each major part of the paper be assigned to its research function without forcing material into an IMRAD heading the journal does not use?

Worked Example

A study can introduce the research question, describe recruitment and analysis in Methods, report outcome estimates in Results, and interpret those estimates and limitations in Discussion.

Sources and evidence

Sources are shown with the role they play in this guide. Historical or style-sensitive claims are kept within the evidence boundary described above.

  1. Preparing a Manuscript for Submission to a Medical Journal — ICMJE (opens in a new tab)International Committee of Medical Journal Editors (ICMJE) · ICMJE manuscript-submission guidance on reporting sources of support/funding that facilitated the work

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